If I'm not wearing it, its either on the table loaded and in a holster as I surf the net and watch TV on the couch with the girlfriend, or its next to my bed loaded and in a holster while we sleep.
If I'm going somewhere where and I won't be out long and for some reason I can't bring it with me, I leave it in the holster in a drawer in my room. If I'm going somewhere for a while and it can't come with (spending the night in NJ for instance) it gets locked up in the lock box, unloaded, and the loop lock around the metal shelf it sits on so that the entire case can't just be run off with, pistol and all.
When I get a few more firearms, I'll invest in a safe. No kids at my place, and I live on the 11th floor in an apartment building with the front door to both the building and my individual apartment locked. I am not worried much about a break in.