What other factors are there that can be proven that don't involve speculation and assumption?
But that's unfair. We know that there are countless "stops" that occur without the kind of trauma Facklerites claim is necessary for a "reliable" stop. They have decreed -- with absolutely no scientific evidence -- that all of these stops are simply "psychological." That's silly. To a Facklerite, "psychological" is a code-word for "stuff we can't explain."
stg58fal hit it right on the head ... do you really think there is no difference between slowly inserting a .45-cal rod into someone and shooting him with a bullet moving 850fps? Do you think it's just myth that tells us a .357 Magnum is more effective than a standard-pressure .38 Special? Especially when the .38 is more likely to get the kind of penetration that the Fackler camp claims is a necessity.
We know that there are any number of physiological responses to various stimuli. A proper choke works by dramatically and quickly disrupting blood flow, tricking the brain into thinking it's suffering a stroke and shutting down. Or look at a taser ... by the Facklerite viewpoint, tasers shouldn't work because they don't make any kind of permanent wound cavity. The Facklerite response to all of this, of course, is that "bullets aren't chokes" and "bullets aren't tasers" but that's just another dodge. You can't claim that "CNS destruction or significant TBV loss are the only means of reliable incapacitation" but admit that other means of incapacitation exist. It's intellectually dishonest.
The fact is, no one has ever studied in detail what happens to a human being as he's being shot. Facklerites have studied corpses and then compared what they find in a corpse (permanent wound cavity) to what they find in a block of jello. That isn't the same thing as measuring the instantaneous effects of a bullet when it strikes someone.
What we do know, however, is that a number of agencies with real experience shooting real people in the real world have found that the Facklerite viewpoint isn't the only path to success.
I happen to carry a "Doc-approved" load, but whether it's on his list or not has nothing to do with my choice. NYPD has been using it and shooting people dead with it for years, which is all the evidence I need that it's effective.